Prof. Ernst Rank and the TUM-IAS team invite the scientists of TUM and their guests for coffee each Wednesday! Just come over to the TUM-IAS after lunch between 1:00 - 2:00 p.m. and have a coffee with us, meet other scientists and listen from time to time to a short talk (10-15 mins) on a recent major TUM publication or issue – aimed specifically at a non-expert audience.
On October 31, 2018, Prof. Ville Kaila (Computational Biocatalysis) will talk about how, for the first time, the mechanism of the enzyme aspoquinolone J (AsqJ), a dioxygenase that activates carbon bonds with oxygen, has been deciphered. The enzyme AsqJ is particularly exciting as it catalyzes a cascade of chemical reactions that ultimately lead to the formation of antibacterial compounds. The findings might open up new options in the production of pharmaceutically active molecules (TUM press release).
Relevant Publication:
S. L. Mader, A. Bräuer, M. Groll, V. R. I. Kaila, “Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.”, Nature Communications 9(1), 1168 (2018) – DOI: 10.1038/s41467-018-03442-2
We look forward to seeing you there!
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An overview of upcoming Wednesday Coffee Talks can be found here: An overview of upcoming Wednesday Coffee Talks can be found here: www.ias.tum.de/events/coffee-talk