TUM-IAS Focal Period 2016
Date: 20.09.2016
Time: 10 am – 5 pm
Location: TUM University Hospital Klinikum rechts der Isar, Lecture Hall Pavillon, Ismaninger Str. 22, 81675 München
Organizers:
- Prof. Dr. med. Dirk H. Busch, Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München; Host: TUM-IAS Focus Group ‘Clinical Cell Purification and Processing’, e-mail: dirk.busch@tum.de
- Prof. Dr. Dietmar W. Hutmacher, Hans Fischer Senior Fellow, TUM-IAS Focus Group ‘Regenerative Medicine’, e-mail: dietmar.hutmacher@qut.edu.au
Motivation and Objectives
Due to promising clinical results in first proof-of-concept trials, Clinical cell purification, processing and therapy (CT) as well as Tissue Engineering and Regenerative Medicine (TE&RM) receive growing attention for the development of innovative and highly effective therapies. Adult tissue stem cells (tSCs) with their high regenerative capacity have the great potential to reconstitute defined human tissues. Major bottlenecks from a translational research point of view are isolation, culture and expansion of tSCs and the maintenance of their potency and self-renewal capacity upon in vivo engraftment. This is becoming especially important when further genetic modification (e.g. recombinant expression of targeting receptors, growth factors or cytokines) is combined with adoptive cell therapy. The regeneration of large volume musculoskeletal tissues requires a scaffold and/or biomimetic hydrogels. Therefore, combining tissue-engineering tool boxes with adoptive cell therapy represents a promising approach to enhance efficacy and predictability of cell therapeutics. At TUM-IAS, leading experts in the field of CT and TE&RM have been brought together within the focus groups ‘Clinical Cell processing and Purification’ and ‘Regenerative Medicine’. Although coming from different research directions, both groups recognized substantial synergy between their activities with unique potential to further advance cell-based therapies.
For the upcoming symposium on ‘Clinical Cell and Tissue Engineering” we have invited the World’s leading experts in this field and want to present the latest research results to the scientific community.
Speakers
- Chiara Bonini – Ospedale San Raffaele, Milan
- Luca Gattinoni – National Institutes of Health
- Robert Guldberg – Georgia Institute of TechnologyKevin Healy – UC Berkeley
- Michael Jensen – Seattle Childere’s Hospital
- Alexander Marson – UC San Francisco
- Stan Riddell – Fred Hutchison Cancer Research Center
- Nico Voelcker – University of South Australia
- Heike Walles - Julius-Maximilians-University Würzburg
