Molecular Imaging

The Focus Group Molecular Imaging is dedicated to search for new avenues in the field of the in vivo quantitative visualization of molecules and molecular events that occur at cellular level. The potential towards clinical translation is huge as the same modalities used in Medical Imaging are used in Molecular Imaging investigations.

The Focus Group consists of Prof. Silvio Aime (Hans Fischer Senior Fellow, Molecular Biotechnology Center, University of Torino), Prof. Markus Schwaiger (Host, Clinic for Nuclear Medicine, TUM), Prof. Axel Haase (Carl von Linde Senior Fellow, Institute of Medical Engineering, TUM) and other researchers at TUM and University of Torino who combine their efforts to set up a most advanced platform in the field of innovative imaging procedures for medical diagnosis. In particular the Focus Group is tackling projects related to the advent of the hybrid PET/MR imaging modality in order to exploit at best the complementarities between the combined modalities.

Doctoral Candidate:
Giaime Rancan (PhD in 2015), Clinic for Nuclear Medicine

Publications by the Focus Group

2015

  • Rancan, Giaime: Optimization Strategies for ParaCEST Contrast Agents in MRI. Dissertation, 2015 more…

2013

  • Castelli, Daniela Delli; Terreno, Enzo; Longo, Dario; Aime, Silvio: Nanoparticle-based chemical exchange saturation transfer (CEST) agents. NMR in Biomedicine 26 (7), 2013, 839-849 more…
  • Catanzaro, Valeria; Gringeri, Concetta V.; Menchise, Valeria; Padovan, Sergio; Boffa, Cinzia; Dastrù, Walter; Chaabane, Linda; Digilio, Giuseppe; Aime, Silvio: A R 2p / R 1p Ratiometric Procedure to Assess Matrix Metalloproteinase-2 Activity by Magnetic Resonance Imaging. Angewandte Chemie International Edition 52 (14), 2013, 3926-3930 more…
  • Delli Castelli, Daniela; Caligara, Maria C.; Botta, Mauro; Terreno, Enzo; Aime, Silvio: Combined High Resolution NMR and 1 H and 17 O Relaxometric Study Sheds Light on the Solution Structure and Dynamics of the Lanthanide(III) Complexes of HPDO3A. Inorganic Chemistry 52 (12), 2013, 7130-7138 more…
  • G. Rancan, D. Delli Castelli, and S. Aime: ParaCEST: imaging pH with high μeff Ln(III) complexes on a 1T permanent magnet. Proc. Int. Soc. Mag. Reson. Med. 21, 2013 more…

2012

  • Ferrauto, Giuseppe; Castelli, Daniela Delli; Terreno, Enzo; Aime, Silvio: In vivo MRI visualization of different cell populations labeled with PARACEST agents. Magn Reson Med 69 (6), 2012, 1703-1711 more…
  • Longo, Dario Livio; Busato, Alice; Lanzardo, Stefania; Antico, Federica; Aime, Silvio: Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent. Magnetic Resonance in Medicine 70 (3), 2012, 859-864 more…
  • Reineri, Francesca; Viale, Alessandra; Ellena, Silvano; Alberti, Diego; Boi, Tommaso; Giovenzana, Giovanni Battista; Gobetto, Roberto; Premkumar, Samuel S. D.; Aime, Silvio: 15 N Magnetic Resonance Hyperpolarization via the Reaction of Parahydrogen with 15 N-Propargylcholine. J. Am. Chem. Soc. 134 (27), 2012, 11146-11152 more…