Engineering Cells for Immune Therapie

Publications by the Focus Group

2021

  • Mathewson, Nathan D.; Ashenberg, Orr; Tirosh, Itay; Gritsch, Simon; Perez, Elizabeth M.; Marx, Sascha; Jerby-Arnon, Livnat; Chanoch-Myers, Rony; Hara, Toshiro; Richman, Alyssa R.; Ito, Yoshinaga; Pyrdol, Jason; Friedrich, Mirco; Schumann, Kathrin; Poitras, Michael J.; Gokhale, Prafulla C.; Gonzalez Castro, L. Nicolas; Shore, Marni E.; Hebert, Christine M.; Shaw, Brian; Cahill, Heather L.; Drummond, Matthew; Zhang, Wubing; Olawoyin, Olamide; Wakimoto, Hiroaki; Rozenblatt-Rosen, Orit; Brastianos, Priscilla K.; Liu, X. Shirley; Jones, Pamela S.; Cahill, Daniel P.; Frosch, Matthew P.; Louis, David N.; Freeman, Gordon J.; Ligon, Keith L.; Marson, Alexander; Chiocca, E. Antonio; Reardon, David A.; Regev, Aviv; Suvà, Mario L.; Wucherpfennig, Kai W.: Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell 184 (5), 2021, 1281-1298.e26 mehr…

2020

  • Schumann, Kathrin; Raju, Siddharth S.; Lauber, Michael; Kolb, Saskia; Shifrut, Eric; Cortez, Jessica T.; Skartsis, Nikolaos; Nguyen, Vinh Q.; Woo, Jonathan M.; Roth, Theodore L.; Yu, Ruby; Nguyen, Michelle L. T.; Simeonov, Dimitre R.; Nguyen, David N.; Targ, Sasha; Gate, Rachel E.; Tang, Qizhi; Bluestone, Jeffrey A.; Spitzer, Matthew H.; Ye, Chun Jimmie; Marson, Alexander: Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. Nature Immunology 21 (11), 2020, 1456-1466 mehr…

2019

  • Lowe, Margaret M.; Boothby, Ian; Clancy, Sean; Ahn, Richard S.; Liao, Wilson; Nguyen, David N.; Schumann, Kathrin; Marson, Alexander; Mahuron, Kelly M.; Kingsbury, Gillian A.; Liu, Zheng; Munoz Sandoval, Priscila; Rodriguez, Robert Sanchez; Pauli, Mariela L.; Taravati, Keyon; Arron, Sarah T.; Neuhaus, Isaac M.; Harris, Hobart W.; Kim, Esther A.; Shin, Uk Sok; Krummel, Matthew F.; Daud, Adil; Scharschmidt, Tiffany C.; Rosenblum, Michael D.: Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. JCI Insight 4 (24), 2019 mehr…
  • Schober, Kilian; Müller, Thomas R.; Gökmen, Füsun; Grassmann, Simon; Effenberger, Manuel; Poltorak, Mateusz; Stemberger, Christian; Schumann, Kathrin; Roth, Theodore L.; Marson, Alexander; Busch, Dirk H.: Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature Biomedical Engineering 3 (12), 2019, 974-984 mehr…

2018

  • Hultquist, Judd F.; Hiatt, Joseph; Schumann, Kathrin; McGregor, Michael J.; Roth, Theodore L.; Haas, Paige; Doudna, Jennifer A.; Marson, Alexander; Krogan, Nevan J.: CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions. Nature Protocols 14 (1), 2018, 1-27 mehr…
  • Roth, Theodore L.; Puig-Saus, Cristina; Yu, Ruby; Shifrut, Eric; Carnevale, Julia; Li, P. Jonathan; Hiatt, Joseph; Saco, Justin; Krystofinski, Paige; Li, Han; Tobin, Victoria; Nguyen, David N.; Lee, Michael R.; Putnam, Amy L.; Ferris, Andrea L.; Chen, Jeff W.; Schickel, Jean-Nicolas; Pellerin, Laurence; Carmody, David; Alkorta-Aranburu, Gorka; del Gaudio, Daniela; Matsumoto, Hiroyuki; Morell, Montse; Mao, Ying; Cho, Min; Quadros, Rolen M.; Gurumurthy, Channabasavaiah B.; Smith, Baz; Haugwitz, Michael; Hughes, Stephen H.; Weissman, Jonathan S.; Schumann, Kathrin; Esensten, Jonathan H.; May, Andrew P.; Ashworth, Alan; Kupfer, Gary M.; Greeley, Siri Atma W.; Bacchetta, Rosa; Meffre, Eric; Roncarolo, Maria Grazia; Romberg, Neil; Herold, Kevan C.; Ribas, Antoni; Leonetti, Manuel D.; Marson, Alexander: Reprogramming human T cell function and specificity with non-viral genome targeting. Nature 559 (7714), 2018, 405-409 mehr…