Julian Grünewald

Fellowship
Rudolf Mößbauer Tenure Track

Appointment
2022

Institution
Technical University Munich

Department
TUM School of Medicine and Health

Focus Group
Gene Editing

Publications as TUM-IAS-Fellow

Holzleitner, Noah; Grünewald, Julian: Machine learning-trained protein domain insertion for the design of switchable proteins. Nature Methods 22 (8), 2025, 1629-1631 mehr… BibTeX Volltext ( DOI )
Vuille, Joanna A.; Tanriover, Cem; Antmen, Ezgi; Micalizzi, Douglas S.; Ebright, Richard Y.; Animesh, Sambhavi; Morris, Robert; Hajizadeh, Soroush; Nicholson, Zachary J.; Russell, Hunter C.; Zaniewski, Eric F.; Wittner, Ben S.; Wesley, Ben K.; Kwak, Ji Eun; Grünewald, Julian; Szalay, Regan N.; Fox, Douglas B.; Yang, Min; Joung, J. Keith; Gulhan, Doga C.; Elia, Andrew E. H.; Haas, Wilhelm; Oh, Eugene; Maheswaran, Shyamala; Haber, Daniel A.: The E3 ligase HECTD4 regulates COX-2-dependent tumor progression and metastasis. Proceedings of the National Academy of Sciences 122 (32), 2025, e2425621122 mehr… BibTeX Volltext ( DOI ) Volltext (mediaTUM)

Mergen, Markus; Abele, Daniela; Koleci, Naile; Schmahl Fernandez, Alba; Sugden, Maya; Holzleitner, Noah; Carr, Andreas; Rieger, Leonie; Leone, Valentina; Reichert, Maximilian; Laugwitz, Karl-Ludwig; Bassermann, Florian; Busch, Dirk H.; Grünewald, Julian; Schmidts, Andrea: Engineering de novo binder CAR-T cell therapies with generative AI. bioRxiv, 2024 mehr… BibTeX Volltext ( DOI ) Volltext (mediaTUM)

Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft. Springer Berlin Heidelberg, 2023 mehr… BibTeX Volltext ( DOI )
Cavazza, Alessia; Hendel, Ayal; Bak, Rasmus O.; Rio, Paula; Güell, Marc; Lainšček, Duško; Arechavala-Gomeza, Virginia; Peng, Ling; Hapil, Fatma Zehra; Harvey, Joshua; Ortega, Francisco G.; Gonzalez-Martinez, Coral; Lederer, Carsten W.; Mikkelsen, Kasper; Gasiunas, Giedrius; Kalter, Nechama; Gonçalves, Manuel A.F.V.; Petersen, Julie; Garanto, Alejandro; Montoliu, Lluis; Maresca, Marcello; Seemann, Stefan E.; Gorodkin, Jan; Mazini, Loubna; Sanchez, Rosario; Rodriguez-Madoz, Juan R.; Maldonado-Pérez, Noelia; Laura, Torella; Schmueck-Henneresse, Michael; Maccalli, Cristina; Grünewald, Julian; Carmona, Gloria; Kachamakova-Trojanowska, Neli; Miccio, Annarita; Martin, Francisco; Turchiano, Giandomenico; Cathomen, Toni; Luo, Yonglun; Tsai, Shengdar Q.; Benabdellah, Karim: Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi. Molecular Therapy Nucleic Acids 34, 2023, 102066 mehr… BibTeX Volltext ( DOI )
Grünewald, Julian; Schmidts, Andrea: A gentler yield of ex vivo-edited T cells. Nature Biomedical Engineering 7 (5), 2023, 607-608 mehr… BibTeX Volltext ( DOI )
Petri, Karl; Grünewald, Julian: An update on prime editing: recent advances and applications. Cell and Gene Therapy Insights 9 (9), 2023, 1359-1365 mehr… BibTeX Volltext ( DOI )

Grünewald, Julian; Miller, Bret R.; Szalay, Regan N.; Cabeceiras, Peter K.; Woodilla, Christopher J.; Holtz, Eliza Jane B.; Petri, Karl; Joung, J. Keith: Engineered CRISPR prime editors with compact, untethered reverse transcriptases. Nature Biotechnology 41 (3), 2022, 337-343 mehr… BibTeX Volltext ( DOI )