Angelika Harbauer studies the metabolism of neurons, with a special focus on mitochondrial biogenesis. Even small disturbances in the energy conversion process can lead to toxic reactive oxygen species; therefore, rigorous mitochondrial quality control is essential for cellular survival. If not addressed adequately, damaged mitochondria can lead to neurodegenerative diseases, most prominently Parkinson’s disease. Her laboratory researches the mechanisms and signals that adapt mitochondrial output to their surroundings to ensure their functionality, specifically in neurons.
ERC Grant for IAS Fellows Angelika Harbauer